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Description
Calnexin Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen Calnexin Synonyms IP90; Major histocompatibility complex class I antigen binding protein p88; p90; CANX Immunogen Synthetic Peptide Location Endoplasmic reticulum Accession P27824 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P, ICC Reactivity Hu Positive Sample HeLa, U 2 OS, MCF7, THP 1, SH SY5Y, HepG2, LNCaP Purification Immunogen Affinity Concentration 0. 5 mg ml Conjugation Unconjugated
Product Specification
| Host | Rabbit |
| Antigen | Calnexin |
| Synonyms | IP90; Major histocompatibility complex class I antigen-binding protein p88; p90; CANX |
| Immunogen | Synthetic Peptide |
| Location | Endoplasmic reticulum |
| Accession | P27824 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Positive Sample | HeLa, U-2 OS, MCF7, THP-1, SH-SY5Y, HepG2, LNCaP |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Hu |
| IHC-P | 1:250 | Hu |
| ICC | 1:500 | Hu |
Background
Calnexin is an integral endoplasmic reticulum (ER) type I transmembrane lectin chaperone that transiently binds newly synthesized monoglucosylated N-glycoproteins through its luminal carbohydrate-binding domain, coordinates sequential folding events with the oxidoreductase ERp57 to form disulfide bonds, retains incompletely folded or misassembled polypeptides in the ER via a cytosolic phosphorylation-regulated retrieval motif that interacts with the Sec61 translocon, and thereby serves as a central quality-control checkpoint that prevents aggregation and premature trafficking, while also participating in ER calcium homeostasis and cellular stress responses such as the unfolded protein response (UPR).
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4.3 ★★★★★
Based on 1210 reviews
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Product Reviews
★★★★★ 5
Solid interactive automatic vibrating dog ball toy
Color: Blue, Color: Blue
Picked up this ITEHZTO interactive automatic vibrating dog ball for our pup and it’s a fun, engaging toy that keeps her entertained. It’s rechargeable with USB, motion-activated, and has a good vibrating/rolling action that gets her chasing and playing on her own. The durable build seems like it can handle some rough play, and it’s a nice size for indoor or outdoor use.
It lights up or vibrates when activated which adds extra excitement, especially during evening playtime. Battery life is decent and recharges quickly. Great for when she needs mental and physical stimulation without me having to throw a ball constantly.
Overall a solid interactive dog toy that does a great job keeping active dogs busy. Good value if your dog loves chasing moving/vibrating toys!
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Reviewed in the United States on April 30, 2026
★★★★★ 4
Built-in USB-C solves the power issue, but it is strictly for moderate chewers
Color: Blue
Got this to keep the high-energy puppy occupied indoors so the older dogs can actually get some peace and quiet. The main issue with most automated electronic pet toys is that they rely on expensive, hard-to-find button cell batteries that die after a single afternoon of use.
This unit utilizes a built-in 300mAh battery with a standard Type-C charging interface. That is a mandatory design feature if you actually want to run the toy daily without going broke replacing power cells. The internal motor generates enough erratic movement to keep a dog's attention, and it actually has the torque to navigate over standard tile, hardwood, and light carpets without instantly stalling out in a corner.
You need to completely understand the physical limitations of what you are unboxing here. The listing explicitly states this is not for heavy chewers, and you need to take that warning seriously. The outer shell is TPU, but the internal chassis housing the electronics is hard ABS plastic. If you hand this to an 80-pound working dog that aggressively shreds thick bones, they are going to crush the housing and destroy the internal motor assembly in about ten minutes.
At roughly 2.5 inches in diameter, it's basically the size of a standard tennis ball. If you use it as intended—as an interactive chasing toy for a puppy or a moderate chewer rather than a heavy-duty chew toy—it functions perfectly. It is a highly practical piece of indoor enrichment gear. Solid return on investment for burning off excess canine energy.
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Reviewed in the United States on May 29, 2026
★★★★★ 5
Pawsitively Stimulating🐾
Color: Blue
When my hooman brought this home, I thought it was fur their computer. After all, it has a plug and lights up. When they placed it on the floor, I was pawsomely surprised. Fur real, this little ball is wierd. It doesn't taste at all like my favorite tennis ball. I was a pawplexed that sometimes when I was finally brave enough to get it and hold it in my mouth, it would start jumping around. I think my hoomans finally found a toy that will keep me busy for a while. Mom is howling with excitement because it kept me interested for a long time. I hope I can sleep tonight. I see mom has plugged in my new toy to keep it "charged"- whatever that means....I never had a toy that came with its own leash before. Mom says she is gonna save the toy until other hoomans come over to keep me from being too ruff with them. You see the video, do I look a dog who could be too ruff?- Sincerely, the family dog, a bona-fido toy reviewer
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Reviewed in the United States on May 3, 2026
★★★★★ 4
Freaks my dogs out.
Color: Blue, Color: Blue
My dogs really don't know what to make of these. They mostly follow it around, staring at it curiously, but semi-afraid to approach it. That, or they'll bark at it. It charges quickly and has multiple modes to engage your pet with. It also locks closed securely ... for the most part.
That said, there are some downsides. This toy is mostly made for smaller dogs. I'd say 40 or 50 pounds max. While the plastic shell feels hard and durable, it's not hard enough for a big dog's jaws. My big bulldog mix bore down on this with his teeth, and I hard the plastic starting to snap. It's tough, but not great if your dog is the type who likes to put the pressure on.
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Reviewed in the United States on May 4, 2026
★★★★★ 5
Best money for a dog toy I've spent in a long time
Color: Blue
This interactive ball is small but packs a lot of fun and playtime for my dog's they go crazy every time we bring it out and turn it on, it lights up has several modes vibrates they love it will be purchasing amount for certain
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Reviewed in the United States on May 9, 2026